Python needs to be installed with the “framework” option:

$ brew install python --framework

Next you need to update the “Current” OS X symbolic link:

$ cd /System/Library/Frameworks/Python.framework/Versions/
$ sudo rm Current
$ sudo ln -s /usr/local/Cellar/python/2.7.1/Frameworks/Python.framework/Versions/Current

If you have to remove your current python installation (installed with homebrew) you may need to reinstall setuptools, pip, virtualenv, virtuelenvwrapper, etc.

For my virtualenvwrapper to work correctly I needed to take these steps and set up my .bashrc file accordingly:

$ cd /usr/local/share
$ ln -s ../Cellar/python/2.7.1/bin python

Update .bashrc:

$ export PATH=/usr/local/share/python:$PATH

Next you must install MacVim from source. Download the latest package, untar and configure:

$ cd b4winckler-macvim-6e6fac5
$ ./configure --enable-gui=macvim --with-features=huge --enable-rubyinterp --enable-pythoninterp --enable-perlinterp --with-python-config-dir=/usr/local/Cellar/python/2.7.1/Frameworks/Python.framework/Versions/2.7/lib/python2.7/config
$ make
$ cp -R src/MacVim/build/Release/MacVim.app /Application

Once this is done everything seemed to work perfect! On my Ubuntu VM I didn’t have to do anything special like this so I mark it up with how Mac OS X handles Frameworks differently from other Unix/Linux systems.

Hope this helps!

Update:

To use this compiled version in your terminal I found this alias helpful:

alias vim='/Applications/MacVim.app/Contents/MacOS/Vim'